Minggu, 10 April 2011

Pathophysiology of Appendicitis

appendicitis - Pathophysiology of Appendicitis


The appendix is a small, tube-like organ attached to the first part of the large intestine, also called the colon. It is located in the lower right area of the abdomen. It has no known function. A blockage inside of the appendix causes appendicitis. The blockage leads to increased pressure, problems with blood flow and inflammation. If the blockage is not treated, the appendix can break open and leak infection into the body.

Pathophysiology of Appendicitis

The main cause of appendicitis is obstuksi blockage which can be caused by hyperplasia of the follicles lympoid is the most common cause of fekalit in appendix lumen. The presence of foreign objects such as: worms, stricture due to fibrosis, as a result of previous inflammation. For another example: malignancy (carcinoid carcinoma).

Appendix obstruction that causes mucus produced by mucous unstoppable, more and more mucus is unstoppable and suppress edema appendix wall and stimulate the tunica serosa and visceral peritoneum. Therefore, the neural appendix with the intestinal thorax X then stimulus is perceived as pain around the umbilicus.

The collected mucus was then infected by the bacteria into pus, and then arise venous flow disturbance, while the artery is not disturbed, the resulting widespread inflammation and the local parietal peritoneum, thus causing pain on the right below, this condition is called acute suppurative appendicitis.

When the arterial flow is disrupted then arise allergens and is called by appendicitis gangrenosa. When the wall acute appendix had burst, called appendicitis perforation. When the omentum adjacent bowel can surround the inflamed or perforated appendix will arise a local time, a condition called as appendicitis abscess. In children, because the omentum is still short and thin, relatively long appendix, the appendix wall is much thinner and stamina is still lacking, as well as in older people because there's been blood vessel disorders, the perforation occurred more quickly. If these infiltrates appendicitis cure the symptoms disappear and then arise in the future will occur with chronic appendicitis.

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